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br Surgical margin in gastric
2018-11-06
Surgical margin in gastric cancer The effect of positive or negative resection margin on the prognosis of gastric cancer was recognized and debated for decades. In a retrospective study by Chen et al, 64 advanced gastric cancer patients with positive resection margin after potentially curative re
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Clinical trials with allogeneic neural cells most
2018-11-06
Clinical trials with allogeneic neural vascular disrupting agent most often involve immunosuppressive treatments (Piccini et al., 2005; Krystkowiak et al., 2007; Sandner et al., 2012), although it is still not fully understood how immunogenic these cells are, whether immunosuppression is a prerequi
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It is not known exactly when the improvements start after
2018-11-06
It is not known exactly when the improvements start after MSC transplantation. We found no differences in the striatal neurodegeneration of transplanted and non-transplanted lesioned rats 24h after the transplantation procedure. Thus, a gap might be necessary between cell transplantation and detecta
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Although the exact mechanism by which WNT levels
2018-11-06
Although the exact mechanism by which WNT3 levels in hESCs predict their differentiation potential is not known, we propose a working model that can explain all of our data so far (Figure 3C). It has been established that the identity of hESCs is mainly determined by the core pluripotency regulatory
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GABAA receptors GABAAR are heteropentameric ion channels wit
2018-11-06
GABAA receptors (GABAAR) are heteropentameric ion channels with prevalent expression on immature cells, including astrocyte-like SVZ cells, TACs and neuroblasts (Platel et al., 2010). Previous studies reveal that GABAAR activation decreases the proliferation of embryonic neocortical progenitors (Hay
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Although H AZK me could be detected by ChIP
2018-11-06
Although H2AZK7me1 could be detected by ChIP at the transcriptional start site of a few differentiation markers (Fgf5, FoxA2, and Hand2) in E14 mES cells and the level of methylation decreased from those genes in response to retinoic acid-induced differentiation, we still do not know what H2AZK7me1
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br Materials and methods br Results br Discussion Murine emb
2018-11-06
Materials and methods Results Discussion Murine embryonic stem purchase PD98059 have been shown to be responsive to IFN-α and IFN-β (Whyatt et al., 1993). The undifferentiated hESC and iPSC showed an attenuated type I interferon response that correspond to high expression of SOCS1, a suppr
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Muscle resident Sca CD cells were
2018-11-06
Muscle-resident Sca-1+CD45− Batimastat were minimally responsive to HFD and/or endurance exercise. A significant reduction in VEGF gene expression was observed in MDSCs in response to HFD, yet no other changes were noted in MDSC relative quantity or the expression of genes related to ECM remodeling
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In the current study we used only gene expression data
2018-11-06
In the current study, we used only gene expression data for the analysis; however, phosphoproteomics data could also be used to assign weights to the signaling interactome for the inference of niche determinants. An important limitation of the method is that it considers only DERs as the sources of
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There are a number of
2018-11-05
There are a number of potential challenges to using iPSC and iPSC-derived atm inhibitor to model human phenotype and disease. Somatic heterogeneity in iPSC lines that can occur during isolation and culture may interfere with examining genetic variants with subtle effects (Fusaki et al., 2009; Intern
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br Experimental Procedures br Author Contributions
2018-11-05
Experimental Procedures Author Contributions Acknowledgments We are grateful to Dr. Makoto Tachibana for providing mouse TT2 and 248-5 ESCs. This research was supported by the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning (no. 2012M3A
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PF 1022A where and are the effective densities of states
2018-11-05
where and are the effective densities of states of electrons and holes in a two-dimensional subband, respectively; Let us assume that the equality is satisfied under optical excitation, and find the dependence of the position of the quasi Fermi levels of electrons and holes on the temperature
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First stage To determine the matrix an external disturbance
2018-11-05
First stage. To determine the matrix ×, an external disturbance is used to successively generate forced resonant vibrations of the beam corresponding to m lower natural frequencies. Let the bending moment applied in the cross-section x=x0, be the external action, then model (6) of an open-circuit
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br Introduction A social gradient in health has been widely
2018-11-05
Introduction A social gradient in health has been widely observed and is considered a common feature of societies, especially in Western countries (Kawachi & Kennedy, 2002; Marmot, 2004). The associations between socioeconomic status (SES) and health have been reported in many countries worldwide
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br Introduction A social gradient in health has been widely
2018-11-05
Introduction A social gradient in health has been widely observed and is considered a common feature of societies, especially in Western countries (Kawachi & Kennedy, 2002; Marmot, 2004). The associations between socioeconomic status (SES) and health have been reported in many countries worldwide
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