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Loss of function mutations in the INa channel subunit
2019-04-29

Loss-of-function mutations in the INa channel α-subunit (SCN5A) is the most common (~20%) etiology of BrS [49]. Recently, SCN10A, a neuronal sodium channel gene encoding Nav1.8 has been identified as a major susceptibility gene (~16%) for BrS [50]. In addition, loss-of-function mutations in the ICa,
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De esta manera el trabajo se centra en
2019-04-29

De esta manera, el trabajo se centra en la discusión sobre las fronteras y territorios en el marco de la globalización y transnacionalización, la configuración de nuevos y viejos espacios simbólicos e identitarios, las interacciones y zonas de contacto existentes entre numerosos conjuntos sociocultu
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br In his Correspondence Samuel Watson refers
2019-04-29

In his Correspondence, Samuel Watson refers to two sets of African countries to support his argument that one cannot necessarily interpret the synthetic control method (SCM) results of our study as causal effects. Increased funding in the past decade has improved healthcare coverage of the popu
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Catheter related bundle care was implemented in our new NICU
2019-04-29

Catheter-related bundle care was implemented in our new NICU on January 1, 2011 due to the new policy of whole intensive care units in our hospital. We did not analyze the true catheter-associated infection rate, but the total numbers of bloodstream infections, lower respiratory tract infections, an
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br Conflict of interest br Acknowledgments
2019-04-29

Conflict of interest Acknowledgments This work was supported by research Grants from the Ministry of Education, Culture, Science and Technology of Japan; Health Science Research Grants from the Ministry of Health, Labor and Welfare of Japan for Clinical Research on Measures for Intractable Dis
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enos inhibitor By inhibiting osteoclast activity one possibl
2019-04-29

By inhibiting osteoclast activity, one possible option relies to bisphosphonates, the synthetic analogs of pyrophosphate that induce osteoclast apoptosis, decrease osteoclast activation and function by inhibition of the mevalonate pathway [32]. Such therapeutic tools have been studied in primary bon
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Burden of disease estimates are foundational to building the
2019-04-29

Burden of disease estimates are foundational to building the investment case for both vaccine and non-vaccine interventions for typhoid fever. Decisions about who would most benefit from metabolic enzymes and at what age rely on a clear epidemiological picture. Our picture of typhoid fever burden re
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Intimate partner violence is highly
2019-04-29

Intimate partner violence is highly prevalent in sub-Saharan Africa and its role in increasing women\'s risk of HIV acquisition is well recognised, although many aspects of the mechanisms through which HIV increases women\'s risk remain unclear. The most important challenge for researchers is to dev
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En n meros posteriores la secci n
2019-04-29

En números posteriores, la sección Vísperas Republicanas consideraba imperativo que Estrada Palma “forme un gobierno incluyente y no favorezca Tivozanib un solo partido”, en el sentido de aminorar las tensiones surgidas entre los aspirantes a ocupar cargos públicos. Paralelo a esta argumentación, lo
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Su acci n en Chiapas fracas no s lo
2019-04-29

Su acción en Chiapas fracasó, no sólo por el rechazo que generó entre los encomenderos sino también entre los religiosos que apoyaban la encomienda en beneficio propio o bien como mecanismo de cristianización acelerado. Cuando Las Casas regresa na+/ca2+ exchanger España, en lo que hace a su batalla
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GS1101 O paratextos que tambi n son
2019-04-29

O paratextos que también son performativos en tanto que discursiva mente intervienen en el presente y tienen la intención de modificarlo, como por ejemplo el epígrafe que acompaña GS1101 la imagen de la revista Futuro: En este aspecto, el abordaje de la revista en tanto fuente documental ha servi
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Assessments of policies to mitigate
2019-04-29

Assessments of policies to mitigate environmental change should specifically consider the potential unintended adverse consequences (co-harms). Some types of biofuels, such as corn alcohol, compete directly with important food crops. Diesel engines were promoted in some countries because of their re
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Under general anesthesia a thoracoscope port of mm in length
2019-04-28

Under general anesthesia, a thoracoscope port of 10mm in length was placed in the third intercostal space with the patient lying on his left side. We attempted to extract the leads while monitoring the area in the vicinity of the SVC. In order to immediately respond to any emergencies, such as vascu
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Ahora a pesar de tener que ser diferente la
2019-04-28

Ahora, cantharidin pesar de tener que ser diferente, la víctima, como manifiesta Girard, para ser “sacrificable”, también necesita tener rasgos en común con la comunidad que sustituye. Fernando Valle sí los tiene. Liang, por ejemplo, ve la caracterización de Fernando en función del anhelo de Altamir
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The primary outcome was local recurrence or metastasis The
2019-04-28

The primary outcome was local recurrence or metastasis. The secondary outcome included functional outcome based on Musculoskeletal Tumor Society (MSTS) score. Data for the study were retrieved from hospital records, maintained oncological files, surgical files, and clinical examination at the most r
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