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The mutation in Caucasian people
2020-12-28
The Δ32 mutation in Caucasian people of European heritage is quite common but extremely rare in Asian and African countries (Huang et al., 1996). We recently reported the presence of this mutation from India (Husain et al., 1998a) and established the complete inheritance pattern (Husain et al., 1998
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The small GTPase Ran regulates karyopherin cargo
2020-12-28
The small GTPase Ran regulates karyopherin–cargo interactions and the directionality of karyopherin-mediated transport. Like other Ras-family GTPases, Ran cycles between GTP- and GDP-bound states, and the two surface loops in Ran, referred to as the switch I and switch II loops, undergo significant
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In recent years neuroimaging studies
2020-12-28
In recent years, neuroimaging studies have increasingly demonstrated acute effects of THC on Z-IETD-FMK function, the vast majority of them involving a cognitive challenge (Bossong et al., 2014b). For example, without affecting performance accuracy, THC caused reductions in activity during encoding
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In our xenograft study Fig Fig we observed that
2020-12-28
In our xenograft study (Fig. 7, Fig. 8), we observed that DYD acts very similarly to progesterone; the initial faster tumor growth in the PGRMC1-transfected MCF7 tumor was not significant compared with that with progesterone, in Sodium Orthovanadate receptor to the greater tumor growth observed wit
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Although it is well established that
2020-12-28
Although it is well established that estrogen and ESR1 mediate numerous reproductive processes, increasing evidence suggests that ESR2 also lays an integral role in reproduction. ESR2 is a mediator in folliculogenesis and may also act by stimulating ovulation and regulating luteinization (Su et al.,
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In countries such as China
2020-12-28
In countries such as China where there is a high commercial production of rice, the use of rice husk ash (RHA) as an alternative cementing material can become a great asset for environmental rehabilitation and address the difficult disposal issues associated with this agricultural waste [23]. RHA po
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br In order to determine
2020-12-28
In order to determine the physiological roles of WT (wild type) EWSR1, Dr. Lee's group established a conventional Ewsr1 KO mouse [38]. Since then, the Ewsr1 KO (−/−) mouse model has successfully been utilized to decipher many important in vivo roles of EWSR1 (Fig. 1). EWSR1 deficiency alters mi
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The present study also showed that EP deficiency and EP
2020-12-26
The present study also showed that EP2 deficiency and EP4 antagonism significantly suppressed psoriatic STA-21 in an imiquimod model. Notably, however, the combined EP2 deficiency and EP4 antagonism did not completely suppress ear swelling in this model, possibly because there is the IL-17–independ
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Nitric oxide synthase NOS is a
2020-12-26
Nitric oxide synthase (NOS) is a predominant enzyme of immune system, which elaborates nitric oxide (NO) from the amino 8-Bromo-cGMP, sodium salt synthesis arginine (Arg). NO mediates vasodilatation, blood pressure regulation, neurotransmission, host defense, and macrophage-mediated immunity, among
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To provide a brief critical evaluation of this technology an
2020-12-26
To provide a brief critical evaluation of this technology and an outlook, we note that performance of SMEPT is critically dependent on each of the components making up this platform, namely the substrate, the enzyme, and the prodrug. With regards to the latter, SMEPT is built on the experience and s
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Diagnosis of NCC can be
2020-12-26
Diagnosis of NCC can be accomplished via imaging techniques and serological confirmatory testing. The best immunodiagnostic test for NCC, the enzyme-linked immunotransfer blot EITB (Tsang et al., 1989), is based on the detection of SecinH3 to one or more of the 7 lentil-lectin glycoproteins (LLGP)
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br Materials and Methods br Results br Discussion
2020-12-26
Materials and Methods Results Discussion Viral infection of eukaryotic N-acetyl D-galactosamine activate signaling pathways both via specific interaction with pattern recognition receptors (TLRs, RIG-I, MDA5) and more nonspecific mechanisms such as accumulation of newly synthesized viral g
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br Acknowledgments br Multicellular organisms respond
2020-12-25
Acknowledgments Multicellular organisms respond rapidly, and adapt to cellular stress to maximize cell survival. The cellular stress response, also called (ISR), is universally conserved and independent of the stressor. ISR induces rapid, transient reprogramming of cellular protein translation
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Tunicamycin br Materials and methods br Statistical analysis
2020-12-25
Materials and methods Statistical analysis All statistical analyses were performed using SPSS software version 20. Protein Tunicamycin data of DNMTs and clinicopathological parameters were collected. Mann-Whitney U Test was used to assess the differential expression of nonparametric data of D
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Famprofazone Cultured cells or mouse lung tissues were
2020-12-25
Cultured cells or mouse lung tissues were harvested and lysed in Radio-Immunoprecipitation Assay (RIPA) buffer (0.05 mol/l Tris–HCl pH 7.4, 0.15 mol/l NaCl, 0.25% deoxycholic acid, 1% NP-40, 1 mmol/l ethylenediamine tetraacetic Famprofazone (EDTA), 1 mmol/l phenylmethylsulfonyl fuoride, 1 μg/ml ap
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