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br Conclusions This study showed that in
2021-01-06

Conclusions This study showed that in EOC cells, tyrosine kinase receptor DDR1 was expressed mainly in EOC (+)-Aphidicolin with an Epithelial phenotype. The repressed expression of DDR1 in EOC cells with Mesenchymal phenotype could be due to the higher CpG methylation levels observed at the promo
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br Conclusion br Acknowledgments br Introduction Arsenic As
2021-01-06

Conclusion Acknowledgments Introduction Arsenic (As) is one of the most toxic metals derived from the natural environment in soil, air and well water. It has two oxidative states: a trivalent form, arsenite, and a pentavalent form, arsenate. The inorganic As is more toxic than organic As. A
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Many studies have used paradigms based on animal models
2021-01-06

Many studies have used paradigms based on animal models to understand human emotional behavior because it appears to be correlated with fear- and anxiety-related defensive patterns in non-human mammals (Blanchard et al., 2001). In this case, defensive reactions are used to study the neural substrate
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Currently phosphodiesterase type PDE inhibitors are used
2021-01-05

Currently, phosphodiesterase type 5 (PDE-5) inhibitors are used widely as the first- line oral treatment for erectile dysfunction of varying causes. Radical prostatectomy for the treatment of prostate cancer is frequently associated with erectile dysfunction, and this type of erectile dysfunction is
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Methylation of histone tails is
2021-01-05

Methylation of histone tails is important in regulating faah inhibitors structure and transcription. Methylation occurs at arginine and at mono-, di- or tri-methylated lysine residues. The reversibility of histone methylation was recently revealed by the identification of two histone demethylases,
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A particularly important system in which Eph ephrin signalin
2021-01-05

A particularly important system in which Eph-ephrin signaling has been widely studied is neural development, in which downstream signal transduction controls neural stem cell (NSC) proliferation, migration, and survival both during early development and in adulthood (19, 20, 21). Furthermore, Eph-ep
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br EBI structure and expression The
2021-01-05

EBI2 structure and expression The gene encoding EBI2 was originally identified together with EBI1 (CCR7) as the most highly upregulated gene in Epstein–Barr virus-infected Burkitt's lymphoma cells [18]. EBI2 belongs to the rhodopsin-like subfamily of seven transmembrane GPCRs [19]. Although it is
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Our results implicate a critical
2021-01-05

Our results implicate a critical role for CXCR-1 in promoting the migration of colonic tumor cells. Expression of this receptor, but not CXCR-2, increased significantly because of the EMT (Fig. 3). Moreover, although Clone A Ro 31-8220 express comparable levels of both IL-8 receptors, only CXCR-1 in
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br Introduction Proteins therapeutic can be defined
2021-01-05

Introduction Proteins therapeutic can be defined as proteins that are either naturally produced in the body or created in the laboratory and introduced into the patient with the aim of improving or curing a pathological condition. They are usually acquired from either microbial trpv4 receptor or
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Materials and methods Construction of the Chk YB b Neo
2021-01-05

Materials and methods Construction of the Chk-YB-1b-Neo vector. Approximately 107 plaques from a chicken genomic library established in EMBL3 vector (Clontech Palo Alto, CA) was screened and one clone containing a 12kb insert was selected. Digestion of this clone with SalI and EcoRI restriction enz
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orexin receptor Abbas et al studied the mitigation of ASR in
2021-01-05

Abbas et al. studied the mitigation of ASR in their corresponding study by incorporating RHA [1]. These researchers used Ordinary Portland Cement (OPC), four different percentages (i.e., 10%, 20%, 30% and 40% by weight of OPC) of RHA and reactive aggregate (sand from Dolomite-limestone rock) in thei
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To our knowledge immunohistochemical analysis for
2021-01-05

To our knowledge, immunohistochemical analysis for proGRP was done in 5 cases [9], [10], [17], [18]. Takagi-Takahashi et al. reported that the tumor salvinorin a were positive for proGRP in one case [9]. Yamaguchi et al. also showed that tumor cells in two patients of ES/PNET with elevated serum pr
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Elevation of plasma glucocorticoids as
2021-01-04

Elevation of plasma glucocorticoids as well as a sympathetic activation are highly adaptive mechanisms allowing the individual to cope in various situations [39]. Novelty-induced increase in locomotor activity, characterizing the bold fish herein, accompanied by elevated glucocorticoids is a well-es
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br Acknowledgments Grant support was provided by
2021-01-04

Acknowledgments Grant support was provided by the Leading Academic Discipline Projects of Shanghai Municipal Education Commission (J5028) (J50201) to Dr. Mi, the China National Science Foundation Project (81072076) to Dr. Mi, the China National Science Foundation Project (31000349) to Dr. Shen, a
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A genomic DNA sequence was retrieved
2021-01-04

A genomic DNA sequence was retrieved (Scaffold_30) from the fugu genomic database ( v3.0), which encodes the homolog of CXCL8 of many other vertebrates and specific primers CXCL8F1 and CXCL8R1 () were designed for 3′-RACE and 5′-RACE PCR, respectively. First-strand thymus cDNA was used as template.
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